In an interview with The Associated Press, a senior member of the Shiite cleric council, Mohammad Asif Mesbah, said the center may have been targeted because it houses the deeply pro-Iranian Afghan Voice news agency. Its owner Sayed Eissa Hussaini Mazari is a strong proponent of Iran and his publication is dominated by Iranian news. Iran is a majority Shiite Muslim nation.

The local Islamic State affiliate has carried out several attacks targeting Shiites in Afghanistan. The IS issued a warning earlier this year following an attack on the Iraqi Embassy in Kabul vowing to target Afghanistan’s Shiites. Since then, the IS has taken credit for at least two attacks on Shiite mosques in Kabul and one in the western city of Herat, killing scores of worshippers.

In a telephone interview with The AP, Taliban spokesman Zabiullah Mujahid denied involvement in Thursday’s attack on the cultural center.

The IS affiliate, made up of Sunni extremists, view Shiites as apostates. The IS in Afghanistan is a toxic mix of Uzbek militants belonging to the Islamic Movement of Uzbekistan who broke with the Taliban, as well as disenchanted insurgents who left the much larger and more well-established Taliban.

As attacks targeting Shiites have increased in Kabul, residents of this area have grown increasingly afraid. Most schools have additional armed guards from among the local population. Still, Ramazandada said security at the cultural center was light.

Afghan president Ashraf Ghani called the attack a “crime against humanity.”

In a statement released by the presidential palace, Ghani said: “The terrorist have killed our people. The terrorists have attacked our mosques, our holy places and now our cultural center.” He called them attacks against Islam and “all human values.”

In a statement, the U.S. ambassador to Afghanistan, John R. Bass, called the attack “horrific” and said “we remain confident the Afghan government and people, supported by their friends and partners, will defeat those behind these terrible acts.”

Separately, Dawlat Abad District Gov. Mohammad Karim said a powerful mine killed six shepherd children ranging in age from 8 to 10 on Wednesday.

Afghanistan has the highest number of mine victims in the world, which along with other roadside bombs, kill or wound an estimated 140 people every month.

Elsewhere, a Taliban attack on a security police post in central Ghazni province Wednesday night left three police dead and one other wounded, said Mohammad Zaman, provincial chief of police. AP